It's intriguing to note that once the DCM-producing mutation K36Q in cTnI was released inside the presence of Ca2+, the simulation showed that Ser 22 and 23 no longer interacted closely with cTnC, in accord with our speculation the Ca2+-cTnC-cTnI N terminus conversation is exclusive and is particularly destabilized instantly https://dickj655vhr8.oneworldwiki.com/user