Conolidine’s analgesic effects stem from its conversation with non-opioid pain pathways. Unlike opioids, which bind to µ-opioid receptors while in the central nervous technique, conolidine modulates alternate molecular targets. A Science Advances study found that conolidine interacts Using the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. By https://beaubhjjk.blogpayz.com/38451961/what-does-alternative-natural-pain-relief-to-replace-traditional-painkillers-mean