Investigate into conolidine has led to discovery of an opioid receptor in the human body called ACKR3/CXCR7. ACKR3 is apparently probably the most wanted target for conolidine, which also disregards the other 4 classical opioid receptors(three). thank you.. A: There is limited details on contraindications between Conolidine and blood https://www.proleviate.com/post/conolidine-an-alternative-natural-pain-relief-to-replace-traditional-painkillers